Criteria
International Classification of Headache Disorders, 3rd edition (ICHD-3)[1]
Under ICHD-3, the diagnostic criteria for MOH are:
Headache occurring on ≥15 days/month in a patient with a preexisting headache disorder, and
Regular overuse for >3 months of one or more drugs that can be taken for acute and/or symptomatic treatment of headache, and
Not better accounted for by another ICHD-3 diagnosis.
Overuse of the acute or symptomatic drug is defined as any one of:
Regular intake of ergotamine on ≥10 days/month for >3 months.
Regular intake of one or more triptans, in any formulation, on ≥10 days/month for >3 months.
Regular intake of acetaminophen on ≥15 days/month for >3 months.
Regular intake of one or more nonsteroidal anti-inflammatory drugs (NSAIDs) other than aspirin (acetylsalicylic acid) on ≥15 days/month for >3 months.
Regular intake of aspirin (acetylsalicylic acid) on ≥15 days/month for >3 months.
Regular intake of any other nonopioid analgesic on ≥15 days/month for >3 months.
Regular intake of one or more opioids on ≥10 days/month for >3 months.
Regular intake of one or more combination-analgesic medications (nonopioid analgesics with opioids, butalbital, and/or caffeine) on ≥10 days/month for >3 months.
Regular intake of any combination of ergotamine, triptans, nonopioid analgesics, and/or opioids on a total of ≥10 days/month for >3 months without overuse of any single drug or drug class alone.
Regular intake of any combination of ergotamine, triptans, nonopioid analgesics, and/or opioids on ≥10 days/month for >3 months. The identity, quantity, and/or pattern of use or overuse of these classes of drug cannot be reliably established.
Regular overuse, on ≥10 days/month for >3 months, of one or more medications other than those described above, taken for acute or symptomatic treatment of headache.
Use of this content is subject to our disclaimer