Prognosis
Prognosis depends on several factors, including performance status, duration of established paraplegia, and number of sites of metastasis at presentation, as well as the primary cancer and the patient's life expectancy before the development of MSCC.[7]
Longer duration of ambulation loss and more severe neurologic deficit (e.g., muscle weakness, bladder and bowel dysfunction) are associated with lower probability of recovery of ambulation and neurologic recovery in patients with symptomatic MSCC.[95][96]
Reports of recurrence rates of MSCC vary. This may depend, at least in part, on treatment modality. For example, radiation therapy after surgery reduces local recurrence compared with surgery alone, and longer-course radiation therapy schedules may be associated with lower in-field recurrence than short-course schedules.[7]
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