The common cold is the most common acute illness in the US, responsible for approximately 37 million (3%) ambulatory care visits each year.[1]Harris AM, Hicks LA, Qaseem A, et al. Appropriate antibiotic use for acute respiratory tract infection in adults: advice for high-value care from the American College of Physicians and the Centers for Disease Control and Prevention. Ann Intern Med. 2016 Mar 15;164(6):425-34.
https://www.acpjournals.org/doi/abs/10.7326/M15-1840
http://www.ncbi.nlm.nih.gov/pubmed/26785402?tool=bestpractice.com
A US study found that 23.6% of adults had experienced a cold in the previous 4 weeks.[2]Bramley TJ, Lerner D, Sames M. Productivity losses related to the common cold. J Occup Environ Med. 2002 Sep;44(9):822-9.
http://www.ncbi.nlm.nih.gov/pubmed/12227674?tool=bestpractice.com
Upper respiratory tract infections, nasal congestion, throat complaints, and cough are responsible for 11% of general practice consultations in other western countries.[3]Fry J, Sandler G. Common diseases. Their nature, prevalence and care. Dordrecht, The Netherlands: Kluwer Academic; 1993. Each year, children have around 6 to 8 colds, and adults have 2 to 4 colds.[3]Fry J, Sandler G. Common diseases. Their nature, prevalence and care. Dordrecht, The Netherlands: Kluwer Academic; 1993.[4]Tupasi TE, de Leon LE, Lupisan S, et al. Patterns of acute respiratory tract infection in children: a longitudinal study in a depressed community in Metro Manila. Rev Infect Dis. 1990 Nov-Dec;12(suppl 8):S940-9.
http://www.ncbi.nlm.nih.gov/pubmed/2270416?tool=bestpractice.com
[5]Cruz JR, Pareja G, de Fernandez A, et al. Epidemiology of acute respiratory tract infections among Guatemalan ambulatory preschool children. Rev Infect Dis. 1990 Nov-Dec;12(suppl 8):S1029-34.
http://www.ncbi.nlm.nih.gov/pubmed/2270400?tool=bestpractice.com
[6]Kvaerner KJ, Nafstad P, Jaakkola JJ. Upper respiratory morbidity in preschool children: a cross-sectional study. Arch Otolaryngol Head Neck Surg. 2000 Oct;126(10):1201-6.
http://jamanetwork.com/journals/jamaotolaryngology/fullarticle/405408
http://www.ncbi.nlm.nih.gov/pubmed/11031406?tool=bestpractice.com
[7]Witek TJ, Ramsey DL, Carr AN, et al. The natural history of community-acquired common colds symptoms assessed over 4-years. Rhinology. 2015 Mar;53(1):81-8.
http://www.ncbi.nlm.nih.gov/pubmed/25756083?tool=bestpractice.com
There are no major sex or ethnicity differences in incidence. Most infections occur in the winter period. The condition is highly contagious, though it is unclear whether the main mode of spread is by hand-to-hand contact, aerosol between people, or contamination of surfaces by aerosol that then transfers the infective pathogen to buccal mucous membranes (e.g., when eating).
Accompanying mortality/morbidity is rare, although common colds are responsible for considerable discomfort, absenteeism from school and work, and healthcare costs.[2]Bramley TJ, Lerner D, Sames M. Productivity losses related to the common cold. J Occup Environ Med. 2002 Sep;44(9):822-9.
http://www.ncbi.nlm.nih.gov/pubmed/12227674?tool=bestpractice.com