Menopause

Menopause is a physiologic event and its timing may be determined genetically. The endocrine changes are permanent, but hot flashes usually resolve in most women within 5 to 10 years. In an observational study, the median total vasomotor symptom duration was 7.4 years, but this varied by ethnicity.[4]Avis NE, Crawford SL, Greendale G, et al. Duration of menopausal vasomotor symptoms over the menopause transition. JAMA Intern Med. 2015 Apr;175(4):531-9. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433164/pdf/nihms686556.pdf http://www.ncbi.nlm.nih.gov/pubmed/25686030?tool=bestpractice.com African-American women reported the longest total vasomotor symptom duration (median, 10.1 years).[4]Avis NE, Crawford SL, Greendale G, et al. Duration of menopausal vasomotor symptoms over the menopause transition. JAMA Intern Med. 2015 Apr;175(4):531-9. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433164/pdf/nihms686556.pdf http://www.ncbi.nlm.nih.gov/pubmed/25686030?tool=bestpractice.com Urogenital atrophy may stay the same or worsen.