Hypoparathyroidism

Outlook varies depending on etiology and severity of hypoparathyroidism.

Temporary or mild postsurgical hypoparathyroidism

Outlook is excellent for patients with temporary hypoparathyroidism. Suppressed but intrinsically normal glands in patients with chronic hypercalcemia usually regain function within days to weeks of surgery. If the gland(s) remaining after neck surgery have been damaged or devascularized but remain viable, they will regain function in weeks to months, usually by 12 months.

Permanent hypoparathyroidism, all etiologies

In the long-term management of patients with little to no remaining parathyroid hormone secretion, management is complicated by the often high doses of calcium and activated vitamin D therapy. Complications include ectopic calcifications, vitamin D intoxication, hypercalcemia, renal stones, and insufficiency if overtreatment occurs. If undertreatment and hypocalcemia occur, then symptoms of hypocalcemia can manifest themselves. There are no long-term data available on life expectancy in patients with hypoparathyroidism.