Complications

Complication
Timeframe
Likelihood
long term
low

Squamous cell carcinoma (SCC) can occasionally develop in chronic DLE lesions.[39]

Multiple methods exist for treating SCC and vary depending on tumor type, size, and location; patient history; and practitioner. They include surgical excision, Mohs micrographic surgery, and radiation therapy.

Squamous cell carcinoma of the skin

variable
medium

Patients with DLE have approximately a 5% to 10% risk of eventually developing systemic lupus erythematosus (SLE).[2] The risk may depend on the extent and distribution of DLE lesions; patients with widespread DLE have a higher rate of immunologic abnormalities and a greater risk of progressing to SLE.

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