Monitoring

In the absence of histopathology, post-treatment measurement of human chorionic gonadotropin (hCG) levels should be performed weekly until normalization of hCG levels or diagnosis of gestational trophoblastic neoplasia (GTN). The duration of monitoring varies by country.[3] The International Federation of Gynecology and Obstetrics recommends monitoring hCG every 1-2 weeks post-treatment until levels return to normal, followed by a single confirmatory normal measurement within a month for partial hydatidiform moles and monthly hCG measurements for 6 months for complete hydatidiform moles.​[4][41]

Close follow-up aims to maximize the detection of postmolar GTN by identifying plateaued or newly rising hCG levels.

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