Complications
Incidence depends on magnitude and duration of ingestion.
High probability in patients with salicylate levels of 75 mg/dL or higher, or with lower levels if ingestion is subacute or chronic.[1]
ARDS in the setting of salicylate poisoning is an indication for urgent hemodialysis.[13][Figure caption and citation for the preceding image starts]: Chest x-ray image of bilateral infiltrates in a patient with ARDSFrom the personal collection of Dr Lorraine Ware; used with permission [Citation ends].
High probability in patients with prolonged corrected QT interval, particularly when combined with bradycardia or extremes of pH.
High probability of seizures in patients with salicylate levels of 75 mg/dL or higher.[1] Seizures can be terminated by giving benzodiazepines, though minute ventilation should be monitored closely. Anticonvulsants are not usually indicated, as the seizures resolve with the resolution of toxicity.
May affect a few patients. Usually resolves with resolution of toxicity.
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