Treatment algorithm
Please note that formulations/routes and doses may differ between drug names and brands, drug formularies, or locations. Treatment recommendations are specific to patient groups: see disclaimer
children
observation
Although, European guidelines suggest surgical correction may be indicated after 12 months, the clinical impression is that some cases will resolve and it is safe to wait for 2 years, unless there is bowel palpable in the groin and provided the testis has been evaluated and there is no evidence of underlying pathology.[19]European Association of Urology. EAU guidelines on paediatric urology. Mar 2023 [internet publication]. https://uroweb.org/guidelines/paediatric-urology
surgery
Elective surgical repair is indicated for persistence of a hydrocele beyond 2 years of age to avoid complications such as incarcerated inguinal hernia.
The surgical approach involves open repair with an inguinal exploration, careful dissection of the hernia sac (processus vaginalis) from the cord structures, and a high ligation of the sac at the internal ring. Although there is no need to fix the distal hydrocele sac, if it remains tense, then it is best to incise it widely and sew it back upon itself to allow better drainage.[17]Lipshultz LI, Thomas AJ, Khera M. Surgical management of male infertility. In: Wein AJ, Kavoussi LR, Novick AC, et al, eds. Campbell-Walsh urology. 9th ed. Philadelphia, PA: WB Saunders; 2007:665.
In hydrocele of the spermatic cord, the cystic mass is excised or unroofed.[15]Al-Kandari AM, Shabaan H, Ibrahim HM, et al. Comparison of outcomes of different varicocelectomy techniques: open inguinal, laparoscopic, and subinguinal microscopic varicocelectomy: a randomized clinical trial. Urology. 2007 Mar;69(3):417-20. http://www.ncbi.nlm.nih.gov/pubmed/17382134?tool=bestpractice.com
Many clinicians perform laparoscopy via the ipsilateral hydrocele sac to investigate whether there is a contralateral patent processus vaginalis.
Bilateral repair is indicated for patients with an open contralateral internal ring, inguinal or scrotal pathology, or increased intraperitoneal fluid (ventriculoperitoneal shunt, peritoneal dialysis).
adolescents
surgery
In most cases, observation is appropriate. If the hydrocele gets very large and uncomfortable, surgical repair is the definitive management. There are different methods for performing surgical hydrocelectomy in adolescents, such as excision of the hydrocele or plication of the hydrocele wall and internal drainage.[20]Cimador M, Castagnetti M, De Grazia E. Management of hydrocele in adolescent patients. Nat Rev Urol. 2010 Jul;7(7):379-85. http://www.ncbi.nlm.nih.gov/pubmed/20548330?tool=bestpractice.com
observation +/- aspiration
Postvaricocelectomy hydroceles should be observed with or without aspiration.[20]Cimador M, Castagnetti M, De Grazia E. Management of hydrocele in adolescent patients. Nat Rev Urol. 2010 Jul;7(7):379-85. http://www.ncbi.nlm.nih.gov/pubmed/20548330?tool=bestpractice.com
surgery
Surgery should be second line for those who do not benefit from conservative management. It is the best therapy for large, persistent postvaricocelectomy hydroceles.
surgery
Complete excision of tunica vaginalis is appropriate treatment.
adults
observation
In adults, once underlying pathology has been excluded, hydroceles can be managed conservatively with reassurance and scrotal support.
surgery or aspiration and sclerotherapy
Surgery may be appropriate if the hydrocele is large or uncomfortable (dragging sensation) or becomes infected.
Excision of the hydrocele sac is appropriate for hydroceles with thick-walled sacs and multiloculated sacs.
Extreme care must be taken to avoid injury to the vas deferens in younger patients to avoid loss of fertility.
Aspiration and sclerotherapy may be an alternative for adult patients who are poor surgical candidates or unwilling to have surgery and fertility is not an issue.[33]Shakiba B, Heidari K, Afshar K, et al. Aspiration and sclerotherapy versus hydrocelectomy for treating hydroceles: a systematic review and meta-analyses. Surg Endosc. 2023 Jul;37(7):5045-51. http://www.ncbi.nlm.nih.gov/pubmed/37277518?tool=bestpractice.com Repeated aspirations without injecting a sclerosing agent have a success rate of 60% in patients with a hydrocele postvaricocelectomy.[35]Zampieri N, El-Dalati G, Ottolenghi A, et al. Percutaneous aspiration for hydroceles after varicocelectomy. Urology. 2009 Nov;74(5):1122-4. http://www.ncbi.nlm.nih.gov/pubmed/19647305?tool=bestpractice.com
A small amount local anesthetic is injected into the skin of the scrotum. A needle is passed into the hydrocele through the anesthetized area and the fluid is removed. After the removal of fluid, a sclerosing agent such as tetracycline, polidocanol, or 95% alcohol may be instilled. A success rate up to 90% was reported by 1 to 4 injections of polidocanol with a complication rate of 30%.[34]Jahnson S, Sandblom D, Holmang S. A randomized trial comparing 2 doses of polidocanol sclerotherapy for hydrocele or spermatocele. J Urol. 2011 Oct;186(4):1319-23. http://www.ncbi.nlm.nih.gov/pubmed/21849198?tool=bestpractice.com Sclerosant may be drained or allowed to be reabsorbed.
Postoperative pain and recurrence are 2 major complications. Recurrent hydroceles tend to be multiloculated.[27]Dogra VS, Gottlieb RH, Oka M, et al. Sonography of the scrotum. Radiology. 2003 Apr;227(1):18-36. http://www.ncbi.nlm.nih.gov/pubmed/12616012?tool=bestpractice.com
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Please note that formulations/routes and doses may differ between drug names and brands, drug formularies, or locations. Treatment recommendations are specific to patient groups. See disclaimer
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