Cochrane Clinical Answers

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Cochrane Clinical Answers (CCAs) provide a readable, digestible, clinically focused entry point to rigorous research from Cochrane systematic reviews. They are designed to be actionable and to inform decision making at the point of care and have been added to relevant sections of the main Best Practice text.

  • How does diclofenac affect outcomes in adults with acute migraine headaches?
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  • In adults with acute migraine headaches, what are the effects of ibuprofen?
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  • What are the benefits and harms of acetaminophen (paracetamol) with or without an antiemetic in adults with acute migraine headaches?
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  • Can topiramate help to prevent episodic migraine in adults?
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  • How does botulinum toxin type A compare with placebo for preventing migraine in adults?
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