Images and videos

Images

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Graft-versus-host disease

Histology of upper gastrointestinal graft-versus-host disease (GVHD) (medium-power photomicrograph of the stomach): Dilated gastric gland containing necrotic/apoptotic debris (arrow), typical of GVHD

Courtesy of Dr Joel Greenson, Professor, Pathology, University of Michigan; used with permission

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Graft-versus-host disease

Histology of lower gastrointestinal graft-versus-host disease (GVHD) (medium-power photomicrograph of colon, severe disease): Almost complete denudation of the mucosa indicative of severe GVHD involving the colon

Courtesy of Dr Joel Greenson, Professor, Pathology, University of Michigan; used with permission

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4

Graft-versus-host disease

Histology of skin graft-versus-host disease (GVHD) (high power): Vacuolar interface dermatitis with rare necrotic keratinocytes (200x, haematoxylin and eosin)

Courtesy of Dr Lori Lowe, Professor, Dermatopathology, University of Michigan; used with permission

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Graft-versus-host disease

Histology of lower gastrointestinal graft-versus-host disease (GVHD) (high-power photomicrograph of colon, mild disease): Numerous apoptotic bodies (arrows) indicative of GVHD involving the colon

Courtesy of Dr Joel Greenson, Professor, Pathology, University of Michigan; used with permission

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3

Graft-versus-host disease

Histology of skin graft-versus-host disease (GVHD) (low power): Vacuolar interface dermatitis at the dermoepidermal junction with involvement of follicular epithelium (100x, haematoxylin and eosin)

Courtesy of Dr Lori Lowe, Professor, Dermatopathology, University of Michigan; used with permission

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Graft-versus-host disease

GVHD pathophysiology

Courtesy of Dr James L.M. Ferrara, Professor, Blood and Marrow Transplantation Program, University of Michigan; used with permission

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2

Graft-versus-host disease

Acute graft-versus-host disease (GVHD) of the skin (grade I)

Courtesy of Dr John Levine, Professor, Blood and Marrow Transplantation Program, University of Michigan; used with permission

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