Emerging treatments
Mycobacterium leprae-bactericidal antibiotics
Two antibiotics have shown to be highly bactericidal against M leprae, and could potentially be included in the multi-drug therapy regimen. These antibiotics are rifapentine, a long-acting rifamycin derivative, and diarylquinoline (R207910).[47][48][49][50]
Single-dose chemotherapy
Single-dose chemotherapy with ROM (rifampicin, ofloxacin, and minocycline) has shown promising preliminary results in paucibacillary leprosy patients with a single lesion.[45] However, further studies are needed.
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