Prognosis

In almost all cases, the prognosis of CLM is entirely benign, although the migrating larvae can cause considerable distress and discomfort. For individuals living in endemic areas with frequent episodes of infection, quality of life may be significantly impaired.[9] Without treatment, migrating larvae will die in the skin after about 2 to 8 weeks, although manifestations have been reported to last for months in some cases.[22]​ Once treated, symptoms rapidly resolve and skin findings disappear, usually within 1 week.[30]

Relapse

Symptoms and skin findings may recur after an initial positive response to treatment, probably because the hookworm larvae were damaged but not completely killed. Relapse usually occurs within weeks of the initial presentation and responds in most cases to a repeated course of treatment.[3][22]​​​[30]

CLM-related folliculitis

Folliculitis due to animal hookworms may require several rounds of anthelmintic therapy.[5]

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