Endemic disease is found throughout tropical coastal regions of the world, especially in the poor communities of South America (particularly Brazil), the Indian subcontinent, and the Caribbean.[6]Gutiérrez de la Solana Dumas J, Alvarez Mesa M, Manzur Katrib J. An outbreak of cutaneous larva migrans [in Spanish]. Rev Cubana Med Trop. 1983 Sep-Dec;35(3):303-16.
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[7]Heukelbach J, Wilcke T, Feldmeier H, et al. Cutaneous larva migrans (creeping eruption) in an urban slum in Brazil. Int J Dermatol. 2004 Jul;43(7):511-5.
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[8]Kannathasan S, Murugananthan A, Rajeshkannan N, et al. Cutaneous larva migrans among devotees of the Nallur temple in Jaffna, Sri Lanka. PLoS One. 2012;7(1):e30516.
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0030516
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[9]Schuster A, Lesshafft H, Talhari S, et al. Life quality impairment caused by hookworm-related cutaneous larva migrans in resource-poor communities in Manaus, Brazil. PLoS Negl Trop Dis. 2011 Nov;5(11):e1355.
http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0001355
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In these regions, it is mostly children who are affected, especially those of low socioeconomic status and those who frequently walk barefoot.[10]Reichert F, Pilger D, Schuster A, et al. Epidemiology and morbidity of hookworm-related cutaneous larva migrans (HrCLM): Results of a cohort study over a period of six months in a resource-poor community in Manaus, Brazil. PLoS Negl Trop Dis. 2018 Jul 19;12(7):e0006662.
https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0006662
http://www.ncbi.nlm.nih.gov/pubmed/30024875?tool=bestpractice.com
Almost all cases of CLM diagnosed in the US occur in tourists who have recently returned from a holiday at a beach destination in the tropics or subtropics, especially the Caribbean, Brazil, Mexico, and Southeast Asia.[4]Davies HD, Sakuls P, Keystone JS. Creeping eruption. A review of clinical presentation and management of 60 cases presenting to a tropical disease unit. Arch Dermatol. 1993 May;129(5):588-91.
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[11]Jelinek T, Maiwald H, Nothdurft HD, et al. Cutaneous larva migrans in travelers: synopsis of histories, symptoms, and treatment of 98 patients. Clin Infect Dis. 1994 Dec;19(6):1062-6.
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[12]Lee VJ, Ong A, Lee NG, et al. Hookworm infections in Singaporean soldiers after jungle training in Brunei Darussalam. Trans R Soc Trop Med Hyg. 2007 Dec;101(12):1214-8.
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It represents one of the most common parasitic infestations in returning travellers.[4]Davies HD, Sakuls P, Keystone JS. Creeping eruption. A review of clinical presentation and management of 60 cases presenting to a tropical disease unit. Arch Dermatol. 1993 May;129(5):588-91.
http://www.ncbi.nlm.nih.gov/pubmed/8481019?tool=bestpractice.com
[13]Gautret P, Cramer JP, Field V, et al. Infectious diseases among travellers and migrants in Europe, EuroTravNet 2010. Euro Surveill. 2012 Jun 28;17(26):pii:20205.
http://www.eurosurveillance.org/content/10.2807/ese.17.26.20205-en
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[14]Stevens MS, Geduld J, Libman M, et al. Dermatoses among returned Canadian travellers and immigrants: surveillance report based on CanTravNet data, 2009-2012. CMAJ Open. 2015 Jan 13;3(1):E119-26.
http://cmajopen.ca/content/3/1/E119.long
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Occasionally, autochthonous cases have been reported in the US, usually from southeastern coastal states such as Florida and South Carolina.[15]Simon MW, Simon NP. Cutaneous larva migrans. Pediatr Emerg Care. 2003 Oct;19(5):350-52.
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[16]Boland TW, Agger WA. Cutaneous larva migrans; recent experience in the La Crossa area. Wis Med J. 1980 Feb;79(2):32-4.
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[17]O'Quinn JC, Dushin R. Cutaneous larva migrans: case report with current recommendations for treatment. J Am Podiatr Med Assoc. 2005 May-Jun;95(3):291-4.
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Most cases in the US occur in adults, although younger age groups are also affected.[3]Tremblay A, MacLean JD, Gyorkos T, et al. Outbreak of cutaneous larva migrans in a group of travellers. Trop Med Int Health. 2000 May;5(5):330-34.
http://onlinelibrary.wiley.com/doi/10.1046/j.1365-3156.2000.00557.x/full
http://www.ncbi.nlm.nih.gov/pubmed/10886795?tool=bestpractice.com
Incidence of CLM is more common in the rainy season, because eggs and larvae survive longer in wet than in dry soil or sand, and disease in dogs and cats is elevated.[18]Heukelbach J, Wilcke T, Meier A, et al. A longitudinal study on cutaneous larva migrans in an impoverished Brazilian township. Travel Med Infect Dis. 2003 Nov;1(4):213-8.
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Climate change and rising global temperatures have been associated with increased incidence of CLM.[19]Choi SH, Beer J, Charrow A. Climate change and the displaced person: how vectors and climate are changing the landscape of infectious diseases among displaced and migrant populations. Int J Dermatol. 2023 May;62(5):681-4.
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