Secondary prevention

Patients should avoid substances known to precipitate attacks (oxidative drugs such as dapsone, primaquine, sulphonamides, and aspirin; broad beans). Patients should be screened for G6PD deficiency before treatment with primaquine for eradication of Plasmodium vivax malaria.[53][40]

In patients undergoing splenectomy, Haemophilus influenzae type b, pneumococcal, and meningococcal vaccinations should be given as early as possible, and long-term antibiotic prophylaxis started to protect against infection by encapsulated bacterial organisms.[50] CDC: ACIP vaccine recommendations and guidelines Opens in new window UK Health Security Agency: Guidance of immunisation of individuals with underlying medical conditions: the green book, chapter 7 Opens in new window

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