Epidemiology
Prevalence is 7 per 1000, and the condition is seen most often in older people.[4] The incidence is increased about 3-fold in denture wearers and almost two-fold in men.[5] Nutritional deficiencies account for approximately 25% of all cases of angular cheilitis. There is an association with anaemia in 11.3% to 31.8% of patients with angular cheilitis.[6]The prevalence of angular cheilitis in patients with HIV infection is between 5.6% to 28.9%.[6] In a study of patients with HIV infection in Brazil, the incidence of angular cheilitis was 13.9%.[7] Of HIV-infected patients, 10% may have an opportunistic infection withCandida albicans, which can present as angular cheilitis.[8] Angular cheilitis was detected in 7.8% of patients with Crohn's disease and 5% of patients with ulcerative colitis.[9]
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