Ichthyosis

Incidence and prevalence rates vary depending on the type of ichthyosis and the population studied. The prevalence of ichthyosis vulgaris, the most common form of ichthyosis, was determined to be about 1 in 250 individuals in a UK population, and 2.29% in the Chinese population.[2]Wells RS, Kerr CB. Clinical features of autosomal dominant and sex-inked ichthyosis in an English population. Br Med J. 1966;1:947-950. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1844863 [3]Lei G, Zhang Y, Hu Y. Investigation on the prevalence of ichthyosis in Sichuan province. Chin J Dermatol. 1992;25:105-106. X-linked ichthyosis occurs in about 1 in 2000 to 6000 males.[2]Wells RS, Kerr CB. Clinical features of autosomal dominant and sex-inked ichthyosis in an English population. Br Med J. 1966;1:947-950. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1844863 The other primary ichthyoses, autosomal recessive congenital ichthyosis and epidermolytic ichthyosis, occur much less frequently, with an estimated prevalence of about 1 in 300,000.[4]Al-Zayir AA, Al-Amro Al-Alakloby OM. Clinico-epidemiological features of primary hereditary ichthyoses in the Eastern province of Saudi Arabia. Int J Dermatol. 2006;45:257-264. http://www.ncbi.nlm.nih.gov/pubmed/16533225?tool=bestpractice.com