Cochrane Clinical Answers
Cochrane Clinical Answers (CCAs) provide a readable, digestible, clinically focused entry point to rigorous research from Cochrane systematic reviews. They are designed to be actionable and to inform decision making at the point of care and have been added to relevant sections of the main Best Practice text.
- Is there randomized controlled trial evidence to support the use of antiretroviral pre-exposure prophylaxis (PrEP) for preventing HIV in high-risk individuals?
- For sexually active women, do topical microbicides prevent sexually transmitted infections (STIs)?
- Does antiretroviral therapy prevent HIV transmission in HIV-discordant couples?
- Can circumcision in men prevent homosexual acquisition of HIV?
- What are the effects of antiretroviral resistance testing for people with HIV?
- Can prospective genetic testing be used to prevent hypersensitivity reactions to drug treatment in adults with HIV type 1?
- How does family planning (with or without HIV prevention) compare with usual care for women living with HIV?
- In severely immunodepressed people, how does fluconazole compare with nystatin for improving outcomes?
- What are the effects of multiple micronutrient supplementation for adolescents and adults with HIV infection?
- How do nutritional interventions affect outcomes in adults with HIV?
- For adults with HIV infection receiving multivitamin supplementation, how does a high dose compare with a standard dose?
- For adults with HIV infection, what are the effects of rapid initiation of antiretroviral therapy (ART)?
- What is the optimal time to initiate antiretroviral therapy in treatment-naive adults with asymptomatic HIV infection?
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