Complications

Complication
Timeframe
Likelihood
short term
medium

An important predictor of outcome in adults. Reported in about 12% of adults with pneumococcal meningitis.[17][116]

Shock

short term
medium

Local inflammatory responses to bacteria, altered cerebral blood flow, and vasculitis lead to cerebral oedema. Lumbar puncture is contraindicated in patients with suspected elevated intracranial pressure (ICP).

Maintain adequate oxygenation and normocarbia. Position patients with heads elevated 30° and in a midline position, and reduce stimuli with sedation and minimal handling.

Treat seizures aggressively.

short term
low

A potential complication of bacterial meningitis that can improve with time.

Normal pressure hydrocephalus

long term
medium

More subtle consequences of bacterial meningitis that may not be apparent for several years after infection.

Survivors of severe infections may have emotional, learning, and behavioural disorders that require multi-disciplinary assessment and treatment.

Assessment of learning difficulty and cognitive delay

variable
medium

Treat aggressively with benzodiazepines. Patients with seizure disorders generally require long-term anticonvulsant therapy.

Overview of seizure disorder

variable
medium

Present in one third of patients. Commonly associated with Haemophilus influenzae and Streptococcus pneumoniae.

Usually asymptomatic and resolves spontaneously.

variable
medium

Sensorineural hearing loss occurs in 25% to 35% of patients after pneumococcal meningitis and in 5% to 10% of patients after Haemophilus influenzae type b meningitis.

Assessment of hearing loss

variable
low

Uncommon but occasionally lethal disease caused by systemic complications. In most cases it is caused by transvenous catheter lines.

Consider in patients with an impaired level of consciousness, seizures, fluctuating focal signs, and stroke.

Deep vein thrombosis

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