Uveitis may affect individuals of any age, sex, or geographical location without preference. Incidence and prevalence in western countries are mostly similar. In developed countries, the incidence of uveitis ranges from approximately 17 to 52 cases per 100,000 per year, while the prevalence ranges from 38 to 714 cases per 100,000.[3]Miserocchi E, Fogliato G, Modorati G, et al. Review on the worldwide epidemiology of uveitis. Eur J Ophthalmol. 2013 Sep-Oct;23(5):705-17.
http://www.ncbi.nlm.nih.gov/pubmed/23661536?tool=bestpractice.com
In one meta-analysis, the pooled incidence of uveitis was 50.45 per 100,000, with geographical region identified as an important source of heterogeneity between studies.[4]García-Aparicio Á, García de Yébenes MJ, Otón T, et al. Prevalence and incidence of uveitis: a systematic review and meta-analysis. Ophthalmic Epidemiol. 2021 Feb 8;:1-8.
http://www.ncbi.nlm.nih.gov/pubmed/33557663?tool=bestpractice.com
In the US, incidence is about 15 cases per 100,000 person-years, although a study carried out in Northern California found the incidence to be higher at 52.4 cases per 100,000 person years.[5]Silverstein A. Changing trends in the etiologic diagnosis of uveitis. Doc Ophthalmol. 2005 Sep;140(3):509-16.
http://www.ncbi.nlm.nih.gov/pubmed/9657289?tool=bestpractice.com
[6]Gritz DG, Wong IG. Incidence and prevalence of uveitis in Northern California; the Northern California Epidemiology of Uveitis Study. Ophthalmology. 2004 Mar;111(3):491-500.
http://www.ncbi.nlm.nih.gov/pubmed/15019324?tool=bestpractice.com
The peak age of presentation of uveitis is between ages 30 and 40 years.[7]Baarsma GS. The epidemiology and genetics of endogenous uveitis: a review. Curr Eye Res. 1992;11 suppl:1-9.
http://www.ncbi.nlm.nih.gov/pubmed/1424734?tool=bestpractice.com
[8]Biswas J, Narain S, Das D, et al. Pattern of uveitis in a referral uveitis clinic in India. Int Ophthalmol. 1996-1997;20(4):223-8.
http://www.ncbi.nlm.nih.gov/pubmed/9112191?tool=bestpractice.com
[9]Merrill PT, Kim J, Cox TA, et al. Uveitis in the southeastern United States. Curr Eye Res. 1997 Sep;16(9):865-74.
http://www.ncbi.nlm.nih.gov/pubmed/9288447?tool=bestpractice.com
Anterior uveitis is the most common form, accounting for at least half of uveitis cases in western countries in one review.[3]Miserocchi E, Fogliato G, Modorati G, et al. Review on the worldwide epidemiology of uveitis. Eur J Ophthalmol. 2013 Sep-Oct;23(5):705-17.
http://www.ncbi.nlm.nih.gov/pubmed/23661536?tool=bestpractice.com
Posterior uveitis is less common, followed by intermediate uveitis.[10]Barisani-Asenbauer T, Maca SM, Mejdoubi L, et al. Uveitis - a rare disease often associated with systemic diseases and infections - a systematic review of 2619 patients. Orphanet J Rare Dis. 2012 Aug 29;7:57.
https://ojrd.biomedcentral.com/articles/10.1186/1750-1172-7-57
http://www.ncbi.nlm.nih.gov/pubmed/22932001?tool=bestpractice.com
[3]Miserocchi E, Fogliato G, Modorati G, et al. Review on the worldwide epidemiology of uveitis. Eur J Ophthalmol. 2013 Sep-Oct;23(5):705-17.
http://www.ncbi.nlm.nih.gov/pubmed/23661536?tool=bestpractice.com
Infectious uveitis is common (30%-60% of cases) in developing countries.[11]Tsirouki T, Dastiridou A, Symeonidis C, et al. A focus on the epidemiology of uveitis. Ocul Immunol Inflamm. 2018;26(1):2-16.
http://www.ncbi.nlm.nih.gov/pubmed/27467180?tool=bestpractice.com
Non-infectious uveitis is more common in developed countries.[3]Miserocchi E, Fogliato G, Modorati G, et al. Review on the worldwide epidemiology of uveitis. Eur J Ophthalmol. 2013 Sep-Oct;23(5):705-17.
http://www.ncbi.nlm.nih.gov/pubmed/23661536?tool=bestpractice.com