Complications
Primary LGV ulcers tend to resolve without consequence, regardless of therapy. The ulcerative nature of LGV may augment transmissibility and susceptibility to HIV and other STIs.[51]
In tertiary LGV, chronic lymphoedema can produce disfiguring anatomical changes in the genitalia that may require plastic reconstructive surgery.
When LGV manifests as an anorectal syndrome in tertiary LGV, chronic proctocolitis may lead to stricture formation and fistula formation. Though rare, if these strictures are not surgically corrected, bowel perforation from obstruction could result in sepsis and death.
In secondary LGV, bubonuli may rupture to create fistulae or sinus tracts. This can complicate healing and ultimately lead to deforming scars and fibrosis.
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