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Last reviewed: 16 Mar 2025
Last updated: 22 Apr 2024

Summary

Definition

History and exam

Key diagnostic factors

  • risk factors
  • open fracture
  • palpable discrepancy in bone contour
  • Battle's sign
  • periorbital ecchymosis
  • bloody otorrhoea
  • cerebrospinal fluid rhinorrhoea
  • facial paralysis, nystagmus, or paraesthesia

Other diagnostic factors

  • evidence of trauma
  • cranial pain or headache
  • nausea/vomiting
  • altered mental state/loss of consciousness
  • abnormal pupillary reflexes
  • hearing loss

Risk factors

  • fall from height
  • motor vehicle accident
  • assault resulting in head trauma
  • gunshots to the head
  • male sex

Diagnostic investigations

Investigations to consider

  • skeletal survey
  • MRI
  • MR angiography
  • beta-2 transferrin assay
  • plain skull x-ray
  • clotting screen

Treatment algorithm

Contributors

Expert advisers

Kevin Tsang, MBBS, BSc (Hons), MRCS (Eng), FRCS (SN)

Consultant Neurosurgeon

Unit Training Lead and Clinical Teacher

Imperial College Healthcare NHS Trust

London

UK

Disclosures

KT declares that he has no competing interests.

Acknowledgements

BMJ Best Practice would like to gratefully acknowledge the previous expert contributors, whose work has been retained in parts of the content:

Demetrios Demetriades MD, PhD, FACS

Professor of Surgery

Director

Division of Trauma and Surgical Intensive Care

LAC+USC Trauma Center

Keck School of Medicine at USC

University of Southern California

Los Angeles

CA

Leslie Kobayashi MD, FACS

Associate Professor of Surgery

Division of Trauma, Surgical Critical Care and Burns

University of California San Diego

San Diego

CA

Disclosures

DD declares that he has no competing interests. LK declares that she has no competing interests.

Peer reviewers

Peter Whitfield, BM, PhD, FRCS Eng, FRCS (SN), FHEA, FAcadMEd

Professor of Neurosurgery

Consultant Neurosurgeon

University Hospitals Plymouth NHS Trust

Plymouth

UK

Disclosures

PW undertakes expert witness work, including in traumatic brain injury cases. He is also lead editor of the text book: Traumatic Brain Injury: a multidisciplinary approach. He receives royalties from Cambridge University Press.

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