Secondary prevention

Sunscreen use is recommended, since sun exposure may activate herpes simplex virus (HSV) that can trigger EM. Radiation and ultraviolet light should be avoided where possible.

In the case of frequent or severe recurrences, HSV titres may suggest the trigger, even when no documented HSV lesions have been found. Oral valaciclovir suppression on a daily basis can be of benefit in preventing disease recurrences. Since the lesions arise quickly, taking valaciclovir treatment doses may be too late to prevent the hypersensitivity reaction.

In the rare setting of drug-related disease, strict drug avoidance is needed to prevent recurrences.[2]​​​[4][5][9]​​

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