Primary prevention
Iodine supplementation of foods has made toxic nodules a relatively uncommon cause of hyperthyroidism in many countries,[22] but iodine deficiency remains a major public health problem worldwide.[21][23] IGN: global scorecard of iodine nutrition in 2021 Opens in new window
Secondary prevention
Iodinated contrast or high-dose iodine supplementation should be avoided in people who have autonomously functioning thyroid nodules.[1] Administration may result in the Jod-Basedow effect (iodine-induced hyperthyroidism), and may also preclude treatment with radioactive iodine for a period of time.
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