Treatment for oppositional defiant disorder (ODD) typically focuses on the most salient impairments for a given individual. Most commonly these involve the patient's interactions with parents, teachers, co-workers, and significant others; improving compliance to directives and reducing antagonism and oppositionality often feature prominently.
Behavioural interventions are the first-line treatment modality for the condition. Emotion regulation skills are usually required to address chronic irritability and enhance overall success with other intervention efforts. Problem-solving skills may be needed to help improve adaptive, successful, and pro-social decision making.
Parents of children with ODD should be involved throughout treatment and may themselves benefit from psychoeducation, behavioural parent training (BPT), and communication skills and, for adolescents, negotiation strategies. Evidence for the management of ODD in adulthood is scarce, but psychotherapy should be considered as appropriate to the individual and their symptomatology.
Behavioural treatment
Children and adolescents
Refer all children and adolescents with ODD (and their families) for behavioural interventions, which are the first-line treatment modality for the condition.[53]National Institute for Health and Care Excellence. Antisocial behaviour and conduct disorders in children and young people: recognition and management. Apr 2017 [internet publication].
https://www.nice.org.uk/guidance/cg158
[55]Steiner H, Remsing L; Work Group on Quality Issues. Practice parameter for the assessment and treatment of children and adolescents with oppositional defiant disorder. J Am Acad Child Adolesc Psychiatry. 2007 Jan;46(1):126-41.
https://www.jaacap.org/article/S0890-8567(09)61969-9/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/17195736?tool=bestpractice.com
[84]Eyberg SM, Nelson MM, Boggs SR. Evidence-based psychosocial treatments for children and adolescents with disruptive behavior. J Clin Child Adolesc Psychol. 2008 Jan;37(1):215-37.
http://www.ncbi.nlm.nih.gov/pubmed/18444059?tool=bestpractice.com
[85]Kaminski JW, Claussen AH, Sims RS, et al. Evidence-based psychosocial treatments for disruptive behaviors in children: update. J Clin Child Adolesc Psychol. 2024 Oct 15:1-30.
https://www.tandfonline.com/doi/full/10.1080/15374416.2024.2405988
http://www.ncbi.nlm.nih.gov/pubmed/39405037?tool=bestpractice.com
[86]McCart MR, Sheidow AJ. Evidence-based psychosocial treatments for adolescents with disruptive behavior. J Clin Child Adolesc Psychol. 2016 Sep-Oct;45(5):529-63.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5055452
http://www.ncbi.nlm.nih.gov/pubmed/27152911?tool=bestpractice.com
Most evidence-based interventions for ODD are provided to families by licensed outpatient mental health providers, although some research has examined alternative deliveries.[53]National Institute for Health and Care Excellence. Antisocial behaviour and conduct disorders in children and young people: recognition and management. Apr 2017 [internet publication].
https://www.nice.org.uk/guidance/cg158
[87]Caldwell DM, Davies SR, Thorn JC, et al. School-based interventions to prevent anxiety, depression and conduct disorder in children and young people: a systematic review and network meta-analysis. NIHR Journals Lib. 2021 Aug;9(8):i-283.
https://www.journalslibrary.nihr.ac.uk/phr/PHR09080
http://www.ncbi.nlm.nih.gov/pubmed/34347403?tool=bestpractice.com
[88]Webster-Stratton C. The Incredible Years® series: a developmental approach. In: Van Ryzin M, Kumpfer KL, Fosco GM, et al, eds. Family-based prevention programs for children and adolescents: theory, research, and large-scale dissemination. New York/London: Psychology Press; 2016:42-67.
https://www.incredibleyears.com/hubfs/The%20Incredible%20Years-%20Resources%20and%20Files/WP%20Files/IY-Series_A-Developmental-Approach.pdf
Central to treatment of ODD is BPT, sometimes referred to as parent management training (PMT). BPT aims to teach effective and supportive parenting skills, counsel on the effective use of contingencies, and improve parent-child communication among other components.[89]Burke JD, Derella OJ, Johnston OG. Chapter 2. Diagnostic issues in oppositional defiant disorder. In: Lochman JE, Matthys W, eds. The Wiley handbook of disruptive and impulse-control disorders. Hoboken, NJ: John Wiley & Sons Ltd; 2017:19-36.
Many effective BPT interventions also include child-directed treatment components. These are typically based on cognitive behavioural therapy (CBT) interventions and may target areas such as emotion-regulation skills, problem-solving skills, or cognitive reframing.[53]National Institute for Health and Care Excellence. Antisocial behaviour and conduct disorders in children and young people: recognition and management. Apr 2017 [internet publication].
https://www.nice.org.uk/guidance/cg158
[90]Evans SC, Weisz JR, Carvalho AC, et al. Effects of standard and modular psychotherapies in the treatment of youth with severe irritability. J Consult Clin Psychol. 2020 Mar;88(3):255-68.
http://www.ncbi.nlm.nih.gov/pubmed/32068426?tool=bestpractice.com
[91]Kazdin AE. Problem-solving skills training and parent management training for conduct disorder. In: Kazdin AE, Weisz JR, eds. Evidence-based psychotherapies for children and adolescents. New York, NY: The Guilford Press; 2003:241-62.
https://psycnet.apa.org/record/2003-88002-013
Specific empirically supported treatments of note include:
Parent-Child Interaction Therapy (PCIT)[92]Zisser A, Eyberg SM. Parent-child interaction therapy and the treatment of disruptive behavior disorders. In: Weisz JR, Kazdin AE, eds. Evidence-based psychotherapies for children and adolescents. 2nd ed. New York, NY: The Guilford Press; 2010:179-93.
https://psycnet.apa.org/record/2010-09488-012
Parent-Child Interaction Therapy
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Incredible Years[93]Webster-Stratton C, Reid MJ. The Incredible Years parents, teachers and children training series: a multifaceted treatment approach for young children with conduct problems. In: Kazdin AE, Weisz JR, eds. Evidence-based psychotherapies for children and adolescents. New York, NY: The Guilford Press; 2003:224-40.
https://psycnet.apa.org/record/2003-88002-012
The Incredible Years®
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Problem-Solving Skills Training and Parent Management Training[91]Kazdin AE. Problem-solving skills training and parent management training for conduct disorder. In: Kazdin AE, Weisz JR, eds. Evidence-based psychotherapies for children and adolescents. New York, NY: The Guilford Press; 2003:241-62.
https://psycnet.apa.org/record/2003-88002-013
[94]Kazdin AE. Problem-solving skills training and parent management training for oppositional defiant disorder and conduct disorder. In: Weisz JR, Kazdin AE, eds. Evidence-based psychotherapies for children and adolescents. 2nd ed. New York, NY: The Guilford Press; 2010:211-26.
https://psycnet.apa.org/record/2010-09488-014
Parent Management Training - Oregon model[95]Forgatch MS, Patterson GR. Parent Management Training - Oregon Model: an intervention for antisocial behavior in children and adolescents. In: Weisz JR, Kazdin AE, eds. Evidence-based psychotherapies for children and adolescents. 2nd ed. New York, NY: The Guilford Press; 2010:159-77.
https://psycnet.apa.org/record/2010-09488-011
Triple P Positive Parenting Program[96]Sanders MR, Kirby JN, Tellegen CL, et al. The Triple P-Positive Parenting Program: a systematic review and meta-analysis of a multi-level system of parenting support. Clin Psychol Rev. 2014 Jun;34(4):337-57.
http://www.ncbi.nlm.nih.gov/pubmed/24842549?tool=bestpractice.com
Triple P Positive Parenting Program
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Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, or Conduct Problems (MATCH ADTC)[90]Evans SC, Weisz JR, Carvalho AC, et al. Effects of standard and modular psychotherapies in the treatment of youth with severe irritability. J Consult Clin Psychol. 2020 Mar;88(3):255-68.
http://www.ncbi.nlm.nih.gov/pubmed/32068426?tool=bestpractice.com
[97]Chorpita BF, Weisz JR. MATCH-ADTC: modular approach to therapy for children with anxiety, depression, trauma, or conduct problems. Satellite Beach, FL: PracticeWise; 2009.
Coping Power.[98]Muratori P, Milone A, Levantini V, et al. Six-year outcome for children with ODD or CD treated with the Coping Power Program. Psychiatry Res. 2019 Jan;271:454-8.
http://www.ncbi.nlm.nih.gov/pubmed/30537668?tool=bestpractice.com
The majority of these interventions have primarily been tested in developed countries such as the US, the UK, and Australia, although some studies also support the use of cognitive behavioural interventions for ODD in developing country settings.[99]Brathwaite R, Ssewamala FM, Sensoy Bahar O, et al; SMART Africa - Uganda Field Team. The longitudinal impact of an evidence-based multiple family group intervention (Amaka Amasanyufu) on oppositional defiant disorder and impaired functioning among children in Uganda: analysis of a cluster randomized trial from the SMART Africa-Uganda scale-up study (2016-2022). J Child Psychol Psychiatry. 2022 Nov;63(11):1252-60.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9256858
http://www.ncbi.nlm.nih.gov/pubmed/34989404?tool=bestpractice.com
[100]Burkey MD, Hosein M, Morton I, et al. Psychosocial interventions for disruptive behaviour problems in children in low- and middle-income countries: a systematic review and meta-analysis. J Child Psychol Psychiatry. 2018 Sep;59(9):982-93.
http://www.ncbi.nlm.nih.gov/pubmed/29633271?tool=bestpractice.com
Note that the historical confounding of ODD and conduct disorder (CD) has impacted the literature on treatment for ODD.
Although most validated treatments for ODD focus on early to middle childhood, the principles of management in children can usually be applied to adolescents.
Adults
Refer adults with ODD to a specialist for consideration of psychotherapeutic interventions. Evidence for the treatment of adults with ODD is scarce; this may be due to the historical tendency to regard ODD as a childhood disorder. Until validated interventions for adult ODD are available, it is reasonable to take inference from evidence-based psychosocial treatments (EBTs) for ODD in childhood. Specifically, intervention components that target emotion-regulation skills, cognitive reframing, and problem-solving skills should be prioritised. Many effective treatments for children and adolescents - especially those grounded in CBT (e.g., dialectical behaviour therapy [DBT], acceptance and commitment therapy [ACT]) - include appropriate components to apply to the treatment of ODD in adulthood.
Pharmacotherapy
Do not give pharmacotherapy for the routine management of behavioural problems to people with ODD in the absence of comorbidities.[9]Hawes DJ, Gardner F, Dadds MR, et al. Oppositional defiant disorder. Nat Rev Dis Primers. 2023 Jun 22;9(1):31.
http://www.ncbi.nlm.nih.gov/pubmed/37349322?tool=bestpractice.com
[53]National Institute for Health and Care Excellence. Antisocial behaviour and conduct disorders in children and young people: recognition and management. Apr 2017 [internet publication].
https://www.nice.org.uk/guidance/cg158
However, effective pharmacotherapy for any associated comorbid conditions (e.g., ADHD or CD) should be considered, which may help to reduce the severity of co-occurring ODD symptoms.[53]National Institute for Health and Care Excellence. Antisocial behaviour and conduct disorders in children and young people: recognition and management. Apr 2017 [internet publication].
https://www.nice.org.uk/guidance/cg158
[55]Steiner H, Remsing L; Work Group on Quality Issues. Practice parameter for the assessment and treatment of children and adolescents with oppositional defiant disorder. J Am Acad Child Adolesc Psychiatry. 2007 Jan;46(1):126-41.
https://www.jaacap.org/article/S0890-8567(09)61969-9/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/17195736?tool=bestpractice.com
[101]Pringsheim T, Hirsch L, Gardner D, et al. The pharmacological management of oppositional behaviour, conduct problems, and aggression in children and adolescents with attention-deficit hyperactivity disorder, oppositional defiant disorder, and conduct disorder: a systematic review and meta-analysis. Part 1: psychostimulants, alpha-2 agonists, and atomoxetine. Can J Psychiatry. 2015 Feb;60(2):42-51.
https://journals.sagepub.com/doi/epdf/10.1177/070674371506000202
http://www.ncbi.nlm.nih.gov/pubmed/25886655?tool=bestpractice.com
[102]Connor DF, Newcorn JH, Saylor KE, et al. Maladaptive aggression: with a focus on impulsive aggression in children and adolescents. J Child Adolesc Psychopharmacol. 2019 Oct;29(8):576-91.
https://www.liebertpub.com/doi/10.1089/cap.2019.0039
http://www.ncbi.nlm.nih.gov/pubmed/31453715?tool=bestpractice.com
See Attention deficit hyperactivity disorder in children and Attention deficit hyperactivity disorder in adults.
Safeguarding
A safeguarding assessment should be conducted as part of the management of ODD. It is recommended that this assessment includes positive and negative aspects of parenting, the parent-child relationship, positive and negative adult relationships within the child's family, including domestic violence, and parental wellbeing (covering mental health issues, substance misuse, and criminal behaviour).[53]National Institute for Health and Care Excellence. Antisocial behaviour and conduct disorders in children and young people: recognition and management. Apr 2017 [internet publication].
https://www.nice.org.uk/guidance/cg158
Risks that may be faced by the patient (e.g., risk of physical, sexual, and emotional abuse) should be assessed and managed. If required, a risk management plan should be developed for self-neglect, exploitation by others, self-harm, or harm to others in line with local protocols.[53]National Institute for Health and Care Excellence. Antisocial behaviour and conduct disorders in children and young people: recognition and management. Apr 2017 [internet publication].
https://www.nice.org.uk/guidance/cg158