Dermatitis herpetiformis

Diagnostic criteria of the European Academy of Dermatology and Venereology[2]Görög A, Antiga E, Caproni M, et al. S2k guidelines (consensus statement) for diagnosis and therapy of dermatitis herpetiformis initiated by the European Academy of Dermatology and Venereology (EADV). J Eur Acad Dermatol Venereol. 2021 Jun;35(6):1251-77. https://onlinelibrary.wiley.com/doi/10.1111/jdv.17183 http://www.ncbi.nlm.nih.gov/pubmed/34004067?tool=bestpractice.com ​

The diagnosis of dermatitis herpetiformis can be made if both major diagnostic criteria are fulfilled:

1. Clinical manifestation of skin lesions which are compatible with dermatitis herpetiformis.

2. Presence of granular immunoglobulin A deposits at the epidermal basement membrane zone at direct immunofluorescence microscopy.