History and exam

Key diagnostic factors

common

presence of risk factors

Ask about risk factors for aspiration pneumonia. However, bear in mind that many patients with pneumonia, even if they have risk factors for aspiration such as swallowing dysfunction, will have a community-acquired, rather than aspiration, pneumonia.[67] Risk factors can be classified according to the underlying mechanism, which can cause aspiration pneumonia due to:

  • Aspiration of oral secretions:

    • Swallowing dysfunction (e.g., stroke, dementia, epilepsy, multiple sclerosis, Parkinson’s disease, motor neuron disease)

    • Impaired conscious level

    • General anaesthetic or oropharyngeal procedures

    • Gastrointestinal (GI) disease (e.g., upper GI surgery, hiatal hernia) and conditions that affect gastric emptying (e.g., obesity, pregnancy)

    • Older age, frailty, and sarcopenia[57][58]

    • Poor cough (e.g., upper airway problems such as pharyngeal pouches and vocal cord palsies, neuromuscular disease)

      • Aspiration pneumonia is a poor prognostic sign in patients with neuromuscular disease[8] 

    • Poor oral hygiene

  • Reflux/vomiting:

    • General anaesthetic or oropharyngeal procedures

    • Poor oral hygiene

    • Recumbent position during enteral feeding

    • Polytrauma

    • Head and neck cancers.

cough

Non-specific symptom. May be present for a week or more after the event.

breathlessness

Non-specific symptom. May be present for a week or more after the event.

Other diagnostic factors

common

history of vomiting

Clinical history is especially important because witnessed aspiration is not seen in the majority of patients.

tachypnoea

Non-specific symptom. Should raise the suspicion for aspiration pneumonia.

foul-smelling breath

Associated with presence of anaerobic bacteria. Highly variable finding in patients with aspiration pneumonia.

crepitations

Highly variable finding in patients with aspiration pneumonia.

frothy or purulent sputum

Non-specific symptom. Should raise the suspicion for aspiration pneumonia.

uncommon

fever

Non-specific symptom. Should raise the suspicion for aspiration pneumonia.

pleuritic chest pain

Non-specific symptom. May be present for a week or more after the event.

delirium

Non-specific symptom. Should raise the suspicion for aspiration pneumonia.

reduced appetite

Non-specific symptom. Should raise the suspicion for aspiration pneumonia.

reduced mobility

Non-specific symptom. Should raise the suspicion for aspiration pneumonia.

general debilitation

Non-specific symptom. Should raise the suspicion for aspiration pneumonia.

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