Emerging treatments

SHIP1 activators

SHIP1 protein is involved in cell signalling for a variety of processes and modulates immunity. A phase 2 study of an oral SHIP1 activator, AQX-1125, showed an overall average improvement of 2.4 in pain score from baseline at 6 weeks.[75]​ However, a larger phase 3 trial showed no difference from placebo after 12 weeks of treatment.[76]

Aloe vera

​Anecdotal reports and one small study (eight patients) suggest that super-concentrated aloe vera capsules may improve symptoms in patients with IC/BPS.[77]​ A phase 2 clinical trial is underway.[78]​​

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