Epidemiology

Prostate cancer is the second most common cancer and the fifth leading cause of cancer mortality in men worldwide.[8] In 2020, it was estimated that approximately 1.4 million new cases of prostate cancer and 375,000 associated deaths occurred worldwide.[8] The highest incidences were reported in Northern and Western Europe, the Caribbean, Australia, New Zealand, Northern America, and Southern Africa.[8] The lowest incidences were reported in Asia and Northern Africa.[8]

Approximately 12.9% of men in the US will be diagnosed with prostate cancer during their lifetime (based on 2017-2019 data).[1] In 2024, it is estimated that there will be 299,010 new cases of prostate cancer in the US.[1] The age-adjusted incidence rate is 116.5 per 100,000 men per year (based on 2017-2021 data).[1] Incidence rate is highest among non-Hispanic black men (188.7 per 100,000) and lowest among non-Hispanic Asian/Pacific Islander men (61.4 per 100,000).[1]

Prostate cancer is most commonly reported in men aged over 50 years; median age at diagnosis in the US is 67 years (based on 2017-2021 data).[1] It is the second leading cause of cancer mortality in men in the US, with an estimated 35,250 prostate cancer-related deaths anticipated in 2024.[1][9]​​

In the UK, prostate cancer is the most common cancer in men. There are about 55,100 new cases every year in the UK (based on 2017-2019 data).[10]​ Incidence rates are approximately twice as high in black men (African, Caribbean, or other black ancestry) compared with white men, and peak at a younger age (2.9 times higher in black men aged <65 years and 1.9 times higher in those aged ≥65 years, based on data from 2013 to 2017).[11] There are approximately 12,000 prostate cancer deaths in the UK every year (2017-2019 data).[10]

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