Metabolic syndrome

The prognosis of patients with respect to cardiovascular disease and the development or progression of type 2 diabetes mellitus is significantly improved with multifactorial intervention. This includes modifying lifestyle (healthy diet and exercise), ameliorating insulin resistance and concomitant hyperglycaemia (weight loss and/or insulin sensitisers), reducing triglyceride and low-density lipoprotein (LDL)-cholesterol levels with an increase in high-density lipoprotein (HDL)-cholesterol, and tightly controlling blood pressure within the recommended targets.