About 70% to 85% of adults experience low back pain (LBP) at some point during their life.[4]Andersson GB. Epidemiological features of chronic low back pain. Lancet. 1999 Aug 14;354(9178):581-5.
http://www.ncbi.nlm.nih.gov/pubmed/10470716?tool=bestpractice.com
Approximately 90% of these individuals will have resolution of symptoms within 3 months of onset, with or without treatment.[4]Andersson GB. Epidemiological features of chronic low back pain. Lancet. 1999 Aug 14;354(9178):581-5.
http://www.ncbi.nlm.nih.gov/pubmed/10470716?tool=bestpractice.com
The majority of patients with acute exacerbations of discogenic back pain will improve by 4 weeks.[173]Pengel LH, Herbert RD, Maher CG, et al. Acute low back pain: systematic review of its prognosis. BMJ. 2003 Aug 9;327(7410):323.
http://www.bmj.com/content/327/7410/323.long
http://www.ncbi.nlm.nih.gov/pubmed/12907487?tool=bestpractice.com
The natural history of LBP suggests that it is reasonable to initially treat all patients conservatively. However, cases presenting with a neurological emergency and those with red flags (night pain, unexplained weight loss, fever, known history of malignancy, intravenous drug user, or tuberculosis exposure) warrant urgent imaging and treatment for the specific underlying pathology. Once all conservative measures have been exhausted or if the symptoms warrant, surgical intervention may be necessary.
Recurrences are common; however, the severity is usually less. Only a small proportion (5%) of people with an acute episode of LBP develop chronic LBP and related disability.[100]Koes BW, van Tulder MW, Thomas S. Diagnosis and treatment of low back pain. BMJ. 2006 Jun 17;332(7555):1430-4.
http://www.bmj.com/content/332/7555/1430?view=long&pmid=16777886
http://www.ncbi.nlm.nih.gov/pubmed/16777886?tool=bestpractice.com
Outcomes after surgery: one study showed superior outcomes for a well-informed and selected group of patients receiving fusion for severe chronic LBP compared with those receiving non-surgical treatment.[145]Fritzell P, Hagg O, Wessberg P, et al. 2001 Volvo Award Winner in Clinical Studies: Lumbar fusion versus nonsurgical treatment for chronic low back pain: a multicenter randomized controlled trial from the Swedish Lumbar Spine Study Group. Spine (Phila Pa 1976). 2001 Dec 1;26(23):2521-32; discussion 2532-4.
http://www.ncbi.nlm.nih.gov/pubmed/11725230?tool=bestpractice.com
Several factors have been analysed with regards to the surgical result after fusion. Interestingly, poor surgical outcome has been correlated with patients receiving workers' compensation, the number of previous low back operations, low income, increased age, and litigation.[174]DeBerard MS, Masters KS, Colledge AL, et al. Outcomes of posterolateral lumbar fusion in Utah patients receiving workers' compensation: A retrospective cohort study. Spine (Phila Pa 1976). 2001 Apr 1;26(7):738-46; discussion 747.
http://www.ncbi.nlm.nih.gov/pubmed/11295891?tool=bestpractice.com
[175]Franklin GM, Haug J, Heyer NJ, et al. Outcome of lumbar fusion in Washington State workers' compensation. Spine (Phila Pa 1976). 1994 Sep 1;19(17):1897-903; discussion 1904.
http://www.ncbi.nlm.nih.gov/pubmed/7997921?tool=bestpractice.com
Another study has shown that smoking, depression, and litigation are predictive factors of a poor outcome despite the successful achievement of fusion.[176]LaCaille RA, DeBerard MS, Masters KS, et al. Presurgical biopsychosocial factors predict multidimensional patient: outcomes of interbody cage lumbar fusion. Spine J. 2005 Jan-Feb;5(1):71-8.
http://www.ncbi.nlm.nih.gov/pubmed/15653087?tool=bestpractice.com
Although there is a continuous evolution in spine surgery with the use of new improved instrumentation and more effective medications, a review of the literature suggests that the results of fusion are still controversial.[145]Fritzell P, Hagg O, Wessberg P, et al. 2001 Volvo Award Winner in Clinical Studies: Lumbar fusion versus nonsurgical treatment for chronic low back pain: a multicenter randomized controlled trial from the Swedish Lumbar Spine Study Group. Spine (Phila Pa 1976). 2001 Dec 1;26(23):2521-32; discussion 2532-4.
http://www.ncbi.nlm.nih.gov/pubmed/11725230?tool=bestpractice.com
[177]Gibson JN, Grant IC, Waddell G. The Cochrane review of surgery for lumbar disc prolapse and degenerative lumbar spondylosis. Spine (Phila Pa 1976). 1999 Sep 1;24(17):1820-32.
http://www.ncbi.nlm.nih.gov/pubmed/10488513?tool=bestpractice.com
[178]Mirza SK, Deyo RA. Systematic review of randomized trials comparing lumbar fusion surgery to nonoperative care for treatment of chronic back pain. Spine. 2007 Apr 1;32(7):816-23.
http://www.ncbi.nlm.nih.gov/pubmed/17414918?tool=bestpractice.com
One systematic review investigating the efficacy of conservative and surgical managements for lumbar disc herniation in athletes found the percentages of athletes returning to their original levels of sporting activity to be 78.9% for conservative treatment, 85.1% for microdiscectomy, and 69.9% for percutaneous discectomy.[179]Iwamoto J, Sato Y, Takeda T, et al. The return to sports activity after conservative or surgical treatment in athletes with lumbar disc herniation. Am J Phys Med Rehabil. 2010 Dec;89(12):1030-5.
http://www.ncbi.nlm.nih.gov/pubmed/20881585?tool=bestpractice.com