Emerging treatments

Interleukin (IL)-2 lozenges

Improves dry mouth symptoms and salivary gland biopsy.

Autologous sera

Autologous sera may improve patient-reported symptoms of dry eye in people with or without Sjogren syndrome compared with artificial tears.[115] However, benefits were inconsistent and autologous sera lacked effect using other objective clinical measures. A small study suggests that diluting autologous serum with sodium hyaluronate may increase its duration and effect on the ocular surface of patients with Sjogren syndrome.[116]

Acupuncture for dry eye

One meta-analysis suggests that acupuncture is more effective than artificial tears for treating dry eye syndrome. However, the included studies showed high heterogeneity.[117]

Use of this content is subject to our disclaimer