Immune thrombocytopenia

Neonates born to a mother with previous or concomitant immune thrombocytopenia are the only population that warrants screening:

• An umbilical cord platelet count is recommended on delivery.

• If levels are low, neonatal platelet count should be repeated as needed; at 3-5 days or, if cord platelet count is <100 × 10⁹/L (<100 × 10³/microlitre), daily until stable.[15]Provan D, Arnold DM, Bussel JB, et al. Updated international consensus report on the investigation and management of primary immune thrombocytopenia. Blood Adv. 2019 Nov 26;3(22):3780-817. https://ashpublications.org/bloodadvances/article/3/22/3780/428877/Updated-international-consensus-report-on-the http://www.ncbi.nlm.nih.gov/pubmed/31770441?tool=bestpractice.com

• The risk of a platelet count <50 × 10⁹/L (<50 × 10³/microlitre) in the neonate is approximately 13%, with one third of these patients having bleeding complications.