Complications
The absence of sex steroids leads to inadequate bone mineralisation. This may result in fractures and osteoporosis later in adult life. All patients with permanent hypogonadism require sex-steroid replacement throughout the reproductive period.
Pubertal delay and short stature due to lack of a growth spurt can result in bullying. A delay in treatment can lead to difficulties in interpersonal relationships, and early treatment must therefore be commenced. Males with anorchidism can be counselled for testicular prosthesis. Those with permanent hypogonadism should receive counselling regarding lack of fertility.
Occurs in up to one third of patients using the patch.
This is a particular problem with intramuscular testosterone preparations. The testosterone dose may need to be reduced.
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