Secondary hyperparathyroidism

The outlook for patients with secondary hyperparathyroidism mirrors the underlying disease. In patients with chronic kidney disease, aggressive electrolyte management optimises the condition; many patients require calcimimetics, a treatment that has reduced the frequency of surgery for this condition. Ultimately, surgery can be performed, which often reduces the level of parathyroid hormone, but is rarely curative. Renal transplantation may be curative, but hyperparathyroidism can persist after the transplant (as tertiary hyperparathyroidism) and cause damage to the new kidney.