Epidemiology

Incidence varies according to factors such as race or ethnic group, genetics, and geographical location.

In Scandinavian countries, incidence rates of 11-24 cases per 100,000 individuals per year have been reported.[8][9]​​​ Estimates from Asia are consistently lower (approximately 1 per 100,000 individuals per year).[9][10]​​ Among African-Americans, sarcoidosis incidence ranges from 18-71 cases per 100,000 individuals per year.[8][11]​ Incidence peaks at a younger age in men than in women (30-50 years versus 50-60 years of age), with some data suggesting that the age at onset is increasing.[8][9][12]

Sarcoidosis prevalence ranges from 1-5 per 100,000 in South Korea to 140-160 per 100,000 in Sweden.[9][13]

Extrathoracic manifestations are more common in certain populations, such as chronic uveitis in black people in the US, lupus pernio in people from Puerto Rico, and erythema nodosum in Europeans.[14]​ Cardiac and ocular sarcoidosis appear to be more common in Japan.[15]​ Women are more likely to have eye and neurological involvement and have erythema nodosum, whereas men are more likely to be hypercalcaemic.[16] Black people are more likely to have skin manifestations (other than erythema nodosum) and have eye, liver, bone marrow, and extrathoracic lymph node involvement.[16]

Use of this content is subject to our disclaimer