Case history
Case history #1
A 50-year-old woman presents with shortness of breath, cough, and painful red skin lesions on the anterior surface of the lower part of both legs. Chest x-ray reveals bilateral hilar lymphadenopathy with pulmonary infiltrates.
Case history #2
A 40-year-old woman presents with skin lesions around her nose, which are indurated plaques with discoloration. She also reports a red, moderately painful right eye with blurred vision and photophobia.
Other presentations
Multi-system involvement is characteristic, but pulmonary involvement usually dominates. Skin, eyes, and peripheral lymph nodes are involved in 15% to 30% of patients. Clinically significant involvement of spleen, liver, heart, central nervous system, bone, or kidney occurs in a few patients. Incidental diagnosis on routine chest x-ray also occurs.
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