Complications

Complication
Timeframe
Likelihood
short term
low

This is a complication of treatment with antipsychotic medication and can develop within hours to days of administration.

It resolves with discontinuation of the antipsychotic agent.

short term
low

This condition is a complication of treatment with antipsychotic medication and can develop within hours to days of administration.

It resolves with discontinuation of the antipsychotic agent.

short term
low

This is a rare but potentially life-threatening complication of treatment with antipsychotic medication. The syndrome is characterised by fever, muscular rigidity, altered mental status, and autonomic dysfunction.

It is considered an emergency and the patient should be taken to the accident and emergency department immediately.

short term
low

These are rare complications of antipsychotic medications and may occur with alpha-2-adrenergic agonist overdose.

short term
low

Can occur with alpha-2-adrenergic agonists.

short term
low

This is a less common, but severe, adverse effect of clonidine or guanfacine when medication is withdrawn without taper.

long term
low

With the exception of tetrabenazine, these conditions are a complication of chronic treatment with antipsychotic medication. They occur more frequently with the first generation (typical) antipsychotics but can occur with both typical and atypical antipsychotics.[76][79] Although some symptoms may improve with discontinuation of the antipsychotic, they can be permanent conditions for which only symptomatic treatment exists.

variable
high

Patients with TS are at higher risk of behavioural problems than those without TS.[7] Parents, teachers, and physicians should regularly monitor for these problems, so that prompt treatment can be instituted.

variable
low

This condition is a complication of treatment with antipsychotic medication, including tetrabenazine.

It resolves with discontinuation of the antipsychotic agent, but may take weeks to months to improve.

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