Monitoring

Because of the increased risk of permanent hypothyroidism developing over time, patients who have had painless thyroiditis and recovered normal thyroid function should be monitored with periodic thyroid-stimulating hormone measurements. There are no data to support specific recommendations for monitoring intervals. However, patients with higher titers of thyroid peroxidase (TPO) antibodies develop permanent hypothyroidism more rapidly than those with low or absent titers. Continued monitoring at least every 5 years for patients with persistent high titer TPO antibodies is advised for sporadic painless thyroiditis. It is recommended to test thyroid function every 3 months for 4 years after the last alemtuzumab dose.[8]

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