Criteria

Minimal criteria that confirm diagnosis[1]

  • Some disturbance of thyroid function:

    • low TSH

    • elevated total T4, total T3, free T4 index, free T4, free T3

    • Total T3:Total T4 ratio <15[32]

    • Free T3:Free T4 ratio <3[17]

  • Clinical and/or laboratory markers of local and/or general inflammatory response:

    • elevated ESR and/or CRP levels

  • Low (<1%) thyroid isotope uptake in the presence of thyroid hormone excess, or the typical hypoechogenic ultrasound with diminished flow

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