Cochrane Clinical Answers

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Cochrane Clinical Answers (CCAs) provide a readable, digestible, clinically focused entry point to rigorous research from Cochrane systematic reviews. They are designed to be actionable and to inform decision making at the point of care and have been added to relevant sections of the main Best Practice text.

  • In people with depression, how do specific behavioral therapies compare with other psychological therapies?
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  • In people with depression, how do behavioral therapies compare with other psychological therapies?
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  • Is there randomized controlled trial evidence to support the use of citalopram in people with depression?
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  • Is there randomized controlled trial evidence to support the use of mirtazapine in people with depression?
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  • What are the effects of newer generation antidepressants in children and adolescents with depressive disorders?
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  • What are the effects of pharmacological and/or psychological continuation and maintenance treatments for adults with persistent depressive disorder?
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  • What are the effects of exercise for improving symptoms in adults with depression?
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  • How does acupuncture compare with no treatment or sham acupuncture for people with depression?
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