Prognosis
Removing the gallbladder and the contained gallstones when biliary pain starts will prevent further biliary attacks and reduce the risk of developing cholecystitis. If the gallbladder perforates, mortality is 30%.[7]
Untreated acute acalculous cholecystitis is life-threatening and is associated with up to 50% mortality.[7]
Generally, there is significant uncertainty in the ability of prognostic factors and risk prediction models in predicting outcomes in patients with acute cholecystitis. Tokyo guidelines 2013 (TG13) grade 3 may be associated with greater mortality than grade 1 severity of acute cholecystitis. Despite the increased risk of mortality in TG13 grade 3 compared with TG13 grade 1, surgery seems to be the preferred option when possible.[36]
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