Astigmatism has an estimated pooled prevalence of 14.9% (95% CI 12.7% to 17.1%) in children and 40.4% (95% CI 34.3% to 46.6%) in adults across all World Health Organization regions.[2]Hashemi H, Fotouhi A, Yekta A, et al. Global and regional estimates of prevalence of refractive errors: systematic review and meta-analysis. J Curr Ophthalmol. 2018 Mar;30(1):3-22.
https://www.sciencedirect.com/science/article/pii/S2452232517300227?via%3Dihub
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Reported prevalence appears to vary by region (27% in northern and western Europe, 11% to 46% in the US, 31% to 58% in South Korea, 54% in Japan, 8% to 62% in China).[3]Zhang J, Wu Y, Sharma B, et al. Epidemiology and burden of astigmatism: a systematic literature review. Optom Vis Sci. 2023 Mar 1;100(3):218-31.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045990
http://www.ncbi.nlm.nih.gov/pubmed/36749017?tool=bestpractice.com
In the US, the condition probably affects about 1 in 3 people.[4]Vitale S, Ellwein L, Cotch MF, et al. Prevalence of refractive error in the United States, 1999-2004. Arch Ophthalmol. 2008 Aug;126(8):1111-9.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772054
http://www.ncbi.nlm.nih.gov/pubmed/18695106?tool=bestpractice.com
The prevalence of astigmatism varies with age. There is a high prevalence (approximately 20%) in the first months of life when the curvature of the cornea is very steep.[5]Howland HC, Sayles N. Photokeratometric and photorefractive measurements of astigmatism in infants and young children. Vision Res. 1985;25(1):73-81.
http://www.ncbi.nlm.nih.gov/pubmed/3984220?tool=bestpractice.com
[6]Friling R, Weinberger D, Kremer I, et al. Keratometry measurements in preterm and full term newborn infants. Br J Ophthalmol 2004 Jan;88(1):8-10.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1771931
http://www.ncbi.nlm.nih.gov/pubmed/14693760?tool=bestpractice.com
As infants grow older, the cornea flattens and the prevalence of high degrees of astigmatism (>1 diopter) decreases, reaching a level of approximately 4.8% in preschool children.[7]Atkinson J, Braddick O, French J. Infant astigmatism: its disappearance with age. Vision Res. 1980;20(11):891-3.
http://www.ncbi.nlm.nih.gov/pubmed/7210516?tool=bestpractice.com
[8]Gwiazda J, Scheinman M, Mohindra I, et al. Astigmatism in children: changes in axis and amount from birth to six years. Invest Ophthalmol Vis Sci. 1984 Jan;25(1):88-92.
http://www.iovs.org/cgi/reprint/25/1/88
http://www.ncbi.nlm.nih.gov/pubmed/6698734?tool=bestpractice.com
Only a few young adults have an astigmatism >1 diopter, but around 63% of young adults ages 20-30 years exhibit ≥0.25 diopter of astigmatism.[9]Satterfield DS. Prevalence and variation of astigmatism in a military population. J Am Optom Assoc. 1989 Jan;60(1):14-8.
http://www.ncbi.nlm.nih.gov/pubmed/2783696?tool=bestpractice.com
With advancing age, the prevalence of astigmatism generally increases because of age-related changes in refractive index gradients within the crystalline lens.[3]Zhang J, Wu Y, Sharma B, et al. Epidemiology and burden of astigmatism: a systematic literature review. Optom Vis Sci. 2023 Mar 1;100(3):218-31.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045990
http://www.ncbi.nlm.nih.gov/pubmed/36749017?tool=bestpractice.com
Astigmatism rates appear broadly comparable by sex.[3]Zhang J, Wu Y, Sharma B, et al. Epidemiology and burden of astigmatism: a systematic literature review. Optom Vis Sci. 2023 Mar 1;100(3):218-31.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045990
http://www.ncbi.nlm.nih.gov/pubmed/36749017?tool=bestpractice.com
Mild astigmatism predominates over moderate/significant astigmatism in both sexes, but severity correlates significantly with age; the prevalence of mild astigmatism increases until age 70 years, when the prevalence of moderate/significant astigmatism begins to increase.[3]Zhang J, Wu Y, Sharma B, et al. Epidemiology and burden of astigmatism: a systematic literature review. Optom Vis Sci. 2023 Mar 1;100(3):218-31.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045990
http://www.ncbi.nlm.nih.gov/pubmed/36749017?tool=bestpractice.com
Several studies have reported increased risk for astigmatism among Hispanic, African-American, and Asian children.[10]Huang J, Maguire MG, Ciner E, et al. Risk factors for astigmatism in the Vision in Preschoolers Study. Optom Vis Sci. 2014 May;91(5):514-21.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004377
http://www.ncbi.nlm.nih.gov/pubmed/24727825?tool=bestpractice.com
[11]McKean-Cowdin R, Varma R, Cotter SA, et al. Risk factors for astigmatism in preschool children: the multi-ethnic pediatric eye disease and Baltimore pediatric eye disease studies. Ophthalmology. 2011 Oct;118(10):1974-81.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186875
http://www.ncbi.nlm.nih.gov/pubmed/21856010?tool=bestpractice.com
Asian people have a relatively high prevalence of astigmatism, perhaps due to the greater tightness of the Asian eyelids and the narrower palpebral apertures.[2]Hashemi H, Fotouhi A, Yekta A, et al. Global and regional estimates of prevalence of refractive errors: systematic review and meta-analysis. J Curr Ophthalmol. 2018 Mar;30(1):3-22.
https://www.sciencedirect.com/science/article/pii/S2452232517300227?via%3Dihub
http://www.ncbi.nlm.nih.gov/pubmed/29564404?tool=bestpractice.com
One prospective cohort study indicated that 19.3% of Singaporean children had astigmatism with a cylinder power of ≥1 diopter.[12]Tong L, Saw SM, Lin Y, et al. Incidence and progression of astigmatism in Singaporean children. Invest Ophthalmol Vis Sci. 2004 Nov;45(11):3914-8.
http://www.iovs.org/cgi/content/full/45/11/3914
http://www.ncbi.nlm.nih.gov/pubmed/15505036?tool=bestpractice.com
In preschool Chinese children, a prevalence of 21.1% was found, and follow-up evaluation in a subset of these children showed that a significant percentage of children had stable and even increased astigmatism.[13]Fan DS, Rao SK, Cheung EY, et al. Astigmatism in Chinese preschool children: prevalence, change, and effect on refractive development. Br J Ophthalmol. 2004 Jul;88(7):938-41.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1772230
http://www.ncbi.nlm.nih.gov/pubmed/15205242?tool=bestpractice.com
Native American people have an increased prevalence of high levels of astigmatism (>1 diopter), possibly due to hereditary and nutritional factors.
Astigmatism has been reported to be a prevalent refractive error in indigenous Brazilians, and other Brazilian populations.[14]Thorn F, Cruz AA, Machado AJ, et al. Refractive status of indigenous people in the northwestern Amazon region of Brazil. Optom Vis Sci. 2005 Apr;82(4):267-72.
http://www.ncbi.nlm.nih.gov/pubmed/15829854?tool=bestpractice.com
[15]Ferraz FH, Corrente JE, Opromolla P, et al. Refractive errors in a Brazilian population: age and sex distribution. Ophthalmic Physiol Opt. 2015 Jan;35(1):19-27.
http://www.ncbi.nlm.nih.gov/pubmed/25345343?tool=bestpractice.com
[16]Schellini SA, Durkin SR, Hoyama E, et al. Prevalence of refractive errors in a Brazilian population: the Botucatu eye study. Ophthalmic Epidemiol. 2009 Mar-Apr;16(2):90-7.
http://www.ncbi.nlm.nih.gov/pubmed/19353397?tool=bestpractice.com