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Last reviewed: 16 Mar 2025
Last updated: 17 Oct 2023

Summary

Definition

History and exam

Key diagnostic factors

  • disclosure of inappropriate contact
  • acute anogenital trauma (any change); transections and absent hymen (in children)
  • sexually transmitted infections

Other diagnostic factors

  • normal genital findings
  • emotional and psychological disorders
  • anogenital lesions
  • labia and perineum injury
  • nongenital injuries
  • vaginal or penile discharge
  • harmful behaviors
  • sexual behavior problems in children
  • chronic medical complaints in children
  • frequent or persistent genitourinary complaints
  • hymenal notches

Risk factors

  • sexual abuse of other children in the home
  • childhood exposure to intimate partner violence
  • adolescents and young women
  • disability
  • poverty or homelessness
  • sex workers
  • living in institutions or areas of conflict
  • use of alcohol or other drugs

Diagnostic tests

1st tests to order

  • forensic specimens
  • testing for Neisseria gonorrhoeae
  • testing for Chlamydia trachomatis
  • serologic tests for syphilis
  • serologic tests for hepatitis B
  • HIV serology
  • urine beta human chorionic gonadotropin
  • testing for trichomonas
  • anogenital culture: herpes simplex virus polymerase chain reaction (PCR)
  • LFT
  • creatinine
  • BUN
  • CBC

Tests to consider

  • HIV confirmatory test
  • HIV RNA PCR
  • Treponema pallidum hemagglutination assay for syphilis
  • serum rapid plasma reagin for syphilis

Treatment algorithm

Contributors

Authors

Sheela Lahoti, MD

Professor

Division of Child Safety and Integrated Care

Department of Pediatrics

University of Texas Medical School at Houston

Houston

TX

Disclosures

SL declares that she has no competing interests.

Rebecca Girardet, MD

Professor

Division of Child Safety and Integrated Care

Department of Pediatrics

University of Texas Medical School at Houston

Houston

TX

Disclosures

RG is a Paediatric Co-Leader for the STI chapter for the Royal College of Paediatrics and Child Health “Purple book.” This is an unpaid advisory position.

Simi Abraham, MD

​Assistant Professor

Division of Child Protection Pediatrics

Department of Pediatrics

University of Texas Medical School at Houston

Houston

TX

Disclosures

SA gives expert testimony in cases and delivers educational lectures on this subject.

Michelle Ruda, MD

Assistant Professor

Division of Child Safety and Integrated Care

Department of Pediatrics

University of Texas Medical School at Houston

Houston

TX

Disclosures

MR declares that she has no competing interests.

Margaret McNeese, MD

Professor

Division of Community and General Medicine

Department of Pediatrics

University of Texas Medical School at Houston

Houston

TX

Disclosures

MM declares that she has no competing interests.

Ashley Gibson, MD

Assistant Professor

Department of Pediatrics

UT Health Houston

Houston

TX

Disclosures

AG is employed by the University of Texas Health Science Center at Houston. She has given expert testimony in cases of child abuse and neglect. She has applied for an institutional grant related to screening for social determinants of health.

Acknowledgements

Dr Sheela Lahoti, Dr Rebecca Girardet, Dr Michelle Ruda, Dr Simi Abraham, Dr Margaret McNeese, and Dr Ashley Gibson would like to gratefully acknowledge Dr Zoe O'Connor for her contribution to this topic, and Dr Christopher Greeley, Dr Shaina Goldsmith, and Dr Jan Welch, previous contributors to this topic.

Disclosures

CG, SG, and JW declare that they have no competing interests.

Peer reviewers

James Lukefahr, MD

Professor of Pediatrics

Child Abuse Division

Department of Pediatrics

University of Texas Health Science Center

San Antonio

TX

Disclosures

JL declares that he has no competing interests.

Suzanne Starling, MD

Medical Director

CHKD-CAP

Professor of Pediatrics

Eastern Virginia Medical School

Norfolk

VA

Disclosures

SS is an author of a reference cited in this topic. SS declares that she has no other competing interests.

Angelo P. Giardino, MD, PhD

Clinical Associate Professor

Pediatrics

Baylor College of Medicine

Medical Director

Texas Children's Health Plan

Houston

TX

Disclosures

APG declares that he has no competing interests.

Ruth Gilbert, MD, MSc, MB ChB

Professor of Clinical Epidemiology

UCL-Institute of Child Health

London

UK

Disclosures

RG declares that she has no competing interests.

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