Chronic pain is common and has a significant impact on quality of life. Prevalence increases with increasing age (especially for pain due to musculoskeletal causes), so the number of people living with chronic pain worldwide will increase as life expectancy increases.[4]GBD 2017 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018 Nov 10;392(10159):1789-858.
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6227754
http://www.ncbi.nlm.nih.gov/pubmed/30496104?tool=bestpractice.com
In a 2016 survey, an estimated 20.4% of adults in the US (50 million) had chronic pain.[5]Dahlhamer J, Lucas J, Zelaya C, et al. Prevalence of chronic pain and high-impact chronic pain among adults: United States, 2016. MMWR Morb Mortal Wkly Rep. 2018 Sep 14;67(36):1001-6.
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6146950
http://www.ncbi.nlm.nih.gov/pubmed/30212442?tool=bestpractice.com
The 2017 Health Survey for England reported that 34% of respondents had chronic pain.[6]Public Health England. Chronic pain in adults 2017. June 2021 [internet publication].
https://www.gov.uk/government/publications/chronic-pain-in-adults-2017
Age-adjusted prevalence is higher in women, adults not currently employed, and people living in deprived areas.[5]Dahlhamer J, Lucas J, Zelaya C, et al. Prevalence of chronic pain and high-impact chronic pain among adults: United States, 2016. MMWR Morb Mortal Wkly Rep. 2018 Sep 14;67(36):1001-6.
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6146950
http://www.ncbi.nlm.nih.gov/pubmed/30212442?tool=bestpractice.com
[6]Public Health England. Chronic pain in adults 2017. June 2021 [internet publication].
https://www.gov.uk/government/publications/chronic-pain-in-adults-2017
The 2017 Global Burden of Disease study concluded that low back pain and migraine are two of the three leading causes of years lived with disability worldwide.[4]GBD 2017 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018 Nov 10;392(10159):1789-858.
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6227754
http://www.ncbi.nlm.nih.gov/pubmed/30496104?tool=bestpractice.com
Myofascial pain occured in about 30% of patients in one general medical clinic and is usually the most common diagnosis in specialty pain clinics.[7]Skootsky SA, Jaeger B, Oye RK. Prevalence of myofascial pain in general internal medicine practice. West J Med. 1989 Aug;151(2):157-60.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1026905/pdf/westjmed00120-0043.pdf
http://www.ncbi.nlm.nih.gov/pubmed/2788962?tool=bestpractice.com
It can occur at any age, but is most common in older people, as well as athletes, hard physical laborers, and sedentary workers.[8]Cao QW, Peng BG, Wang L, et al. Expert consensus on the diagnosis and treatment of myofascial pain syndrome. World J Clin Cases. 2021 Mar 26;9(9):2077-89.
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8017503
http://www.ncbi.nlm.nih.gov/pubmed/33850927?tool=bestpractice.com
Osteoarthritis is one of the most common chronic pain disorders. Estimates of prevalence of arthritis in a 2002 survey were 8% to 16% of the population in Europe and the US; prevalence of osteoarthritis is likely to have increased since then.[4]GBD 2017 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018 Nov 10;392(10159):1789-858.
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6227754
http://www.ncbi.nlm.nih.gov/pubmed/30496104?tool=bestpractice.com
[9]Reginster JY. The prevalence and burden of arthritis. Rheumatology (Oxford). 2002 Apr;41 Supp 1:3-6.
https://academic.oup.com/rheumatology/article/41/suppl_1/3/2255506
http://www.ncbi.nlm.nih.gov/pubmed/12173279?tool=bestpractice.com
Neuropathic pain has been reported to be the 14th most common pain complaint seen in general practice.[10]Hasselström J, Liu-Palmgren J, Rasjö-Wrååk G. Prevalence of pain in general practice. Eur J Pain. 2002;6(5):375-85.
http://www.ncbi.nlm.nih.gov/pubmed/12160512?tool=bestpractice.com
Accurate estimates of the prevalence of neuropathic pain are difficult to obtain due to its heterogeneous nature; surveys using screening tools have produced estimates of between 2% and 12%.[11]Smith BH, Torrance N, Ferguson JA, et al. Towards a definition of refractory neuropathic pain for epidemiological research: an international Delphi survey of experts. BMC Neurol. 2012 May 28;12:29.
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC3476440
http://www.ncbi.nlm.nih.gov/pubmed/22640002?tool=bestpractice.com
[12]VanDenKerkhof EG, Mann EG, Torrance N, et al. An epidemiological study of neuropathic pain symptoms in Canadian adults. Pain Res Manag. 2016;2016:9815750.
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4904601
http://www.ncbi.nlm.nih.gov/pubmed/27445636?tool=bestpractice.com
Fibromyalgia prevalence in the general population may vary between 0.2% and 6.6%.[13]Marques AP, Santo ASDE, Berssaneti AA, et al. Prevalence of fibromyalgia: literature review update. Rev Bras Reumatol Engl Ed. 2017 Jul - Aug;57(4):356-63.
https://www.sciencedirect.com/science/article/pii/S2255502117300056?via%3Dihub
http://www.ncbi.nlm.nih.gov/pubmed/28743363?tool=bestpractice.com
Prevalence is higher in women than in men. Using data from national registries, an estimated 5 million adults in the US have fibromyalgia.[14]Lawrence RC, Felson DT, Helmick CG, et al. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II. Arthritis Rheum. 2008 Jan;58(1):26-35.
https://onlinelibrary.wiley.com/doi/full/10.1002/art.23176
http://www.ncbi.nlm.nih.gov/pubmed/18163497?tool=bestpractice.com
Age of onset is typically between 20 and 60 years, with an average age of 35 years; prevalence increases with age.
Headache is among the top 10 reasons for women to seek a primary care office visit in national surveys in the US.[15]Brett KM, Burt CW. Utilization of ambulatory medical care by women: United States, 1997-98. Vital Health Stat 13. 2001 Jul;(149):1-46.
https://www.cdc.gov/nchs/data/series/sr_13/sr13_149.pdf
http://www.ncbi.nlm.nih.gov/pubmed/11478128?tool=bestpractice.com
Even though tension-type headache is the most common chronic headache identified in community surveys, migraine is most commonly reported among patients seeking headache treatment.[16]Rasmussen BK, Jensen R, Schroll M, et al. Epidemiology of headache in a general population - a prevalence study. J Clin Epidemiol. 1991;44(11):1147-57.
http://www.ncbi.nlm.nih.gov/pubmed/1941010?tool=bestpractice.com
[17]Tepper SJ, Dahlöf CG, Dowson A, et al. Prevalence and diagnosis of migraine in patients consulting their physician with a complaint of headache: data from the Landmark Study. Headache. 2004 Oct;44(9):856-64.
http://www.ncbi.nlm.nih.gov/pubmed/15447694?tool=bestpractice.com
Worldwide, an estimated 2.3 billion people have tension-type headache and 1.3 billion have migraine; the latter is the leading cause of disability among neurologic disorders.[4]GBD 2017 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018 Nov 10;392(10159):1789-858.
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6227754
http://www.ncbi.nlm.nih.gov/pubmed/30496104?tool=bestpractice.com
The prevalence of cluster headache has been estimated at around one person in 500.[18]Russell MB. Epidemiology and genetics of cluster headache. Lancet Neurol. 2004 May;3(5):279-83.
http://www.ncbi.nlm.nih.gov/pubmed/15099542?tool=bestpractice.com