Complications

Complication
Timeframe
Likelihood
short term
medium

Due to reduced fluid intake secondary to the painful mouth ulcers. Adequate fluid replacement (oral or intravenous) according to the patient's age and clinical condition will be required.

short term
medium

Patients with localized or diffuse spreading skin erythema and/or persistent fever should be evaluated for infection and considered for empiric oral antibiotic coverage.

short term
low

Infection with EV71 may lead to this complication.

An acute or subacute onset of a febrile illness, altered mental status, focal neurologic abnormalities, and seizures raises suspicion for this condition.

The patient should be admitted to the hospital for symptomatic and supportive treatment.

short term
low

Infection with EV71 may lead to this complication.

The patient will have limb weakness.

The patient should be admitted to the hospital for symptomatic and supportive treatment.

short term
low

Infection with EV71 may lead to aseptic meningitis.

Viral meningitis may cause fever, headache, stiff neck, or back pain.

The patient should be admitted to the hospital for symptomatic and supportive treatment.

short term
low

Infection with EV71 may lead to this complication.

Symptoms may include chest pain, dyspnea, orthopnea, syncope, fatigue, and palpitations.

The patient should be admitted to the hospital for symptomatic and supportive treatment.

short term
low

Infection with EV71 may lead to these complications.

The patient will have shortness of breath and respiratory distress.

The patient should be admitted to the hospital for symptomatic and supportive treatment.

long term
low

Can occur when a woman contracts EV71 infection during her pregnancy.[19]

Fetal damage can occur during gestation, and infection can be associated with numerous congenital abnormalities and death.

long term
low

Can occur when a woman has hand-foot-and-mouth disease caused by coxsackievirus A16 during pregnancy.[20]

Miscarriage

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