Criteria
Duration of infection
Standard infection:
Typically self-limiting symptoms, resolving by approximately 2 to 3 weeks
Complications may occur in certain patient populations (e.g., pregnant women and people with increased red blood cell turnover/destruction).
Persistent infection:
May occur in people with immunosuppression (e.g., patients with HIV, people receiving chemotherapy or immunosuppression following transplant, or patients with congenital immunodeficiencies)
May not present with classic erythema infectiosum, but with a chronic anemia
Antibodies to virus are usually absent with often high viral levels in the circulation
Symptoms last longer than the standard duration of infection, for example, at least 3 to 4 weeks.
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