International guidelines

Rest of the world

International classification of sleep disorders, 3rd edition, text revision (ICSD-3-TR)​[7]

Published by:American Academy of Sleep Medicine

Last published:2023

Management of restless legs syndrome: an updated algorithm​​[23]

Published by:Restless Legs Syndrome Foundation

Last published:2021

The appropriate use of opioids in the treatment of refractory restless legs syndrome[37]

Published by:Restless Legs Syndrome Foundation

Last published:2018

Evidence-based and consensus clinical practice guidelines for the iron treatment of restless legs syndrome/Willis-Ekbom disease in adults and children[27]

Published by:International Restless Legs Syndrome Study Group (IRLSSG)

Last published:2018

Treatment of restless legs syndrome in adults[2]

Published by:American Academy of Neurology

Last published:2016 (reaffirmed 2022)

Guidelines for the first-line treatment of restless legs syndrome/Willis–Ekbom disease, prevention and treatment of dopaminergic augmentation[26]

Published by:International Restless Legs Syndrome Study Group; European Restless Legs Syndrome Study Group; Restless Legs Syndrome Foundation

Last published:2016

Consensus clinical practice guidelines for the diagnosis and treatment of restless legs syndrome/Willis-Ekbom disease during pregnancy and lactation[46]

Published by:International Restless Legs Syndrome Study Group (IRLSSG)

Last published:2015

Restless legs syndrome/Willis-Ekbom disease diagnostic criteria[1]

Published by:International Restless Legs Syndrome Study Group

Last published:2014

The treatment of restless legs syndrome and periodic limb movement disorder in adults - an update for 2012: practice parameters with an evidence-based systematic review and meta-analyses​[35]

Published by:American Academy of Sleep Medicine

Last published:2012

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