The prevalence of immunoglobulin E-mediated food allergy in the population varies between 2% and 10%.[3]Sampson HA, Aceves S, Bock SA, et al. Food allergy: a practice parameter update - 2014. J Allergy Clin Immunol. 2014 Nov;134(5):1016-25;e43.
https://www.jacionline.org/article/S0091-6749(14)00672-1/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/25174862?tool=bestpractice.com
[4]Sicherer SH, Leung DY. Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in 2008. J Allergy Clin Immunol. 2009 Feb;123(2):319-27.
http://www.ncbi.nlm.nih.gov/pubmed/19203656?tool=bestpractice.com
[5]Chafen JJ, Newberry SJ, Riedl MA, et al. Diagnosing and managing common food allergies: a systematic review. JAMA. 2010 May 12;303(18):1848-56.
http://www.ncbi.nlm.nih.gov/pubmed/20460624?tool=bestpractice.com
In one cross-sectional survey of US adults, almost 19% self-reported a food allergy.[6]Gupta RS, Warren CM, Smith BM, et al. Prevalence and severity of food allergies among US adults. JAMA Netw Open. 2019 Jan 4;2(1):e185630.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324316
http://www.ncbi.nlm.nih.gov/pubmed/30646188?tool=bestpractice.com
However, only 10.8% had a convincing food allergy.
Food allergy is greater in the pediatric population than in adults, with estimates of 6% to 8% in children under 5 years and 3% to 4% in adults.[7]Young E, Stoneham MD, Petruckevitch A, et al. A population study of food intolerance. Lancet. 1994 May 7;343(8906):1127-30.
http://www.ncbi.nlm.nih.gov/pubmed/7910231?tool=bestpractice.com
[8]Bock SA. Prospective appraisal of complaints of adverse reactions to foods in children during the first 3 years of life. Pediatrics. 1987 May;79(5):683-8.
http://www.ncbi.nlm.nih.gov/pubmed/3575022?tool=bestpractice.com
[9]Bock SA, Atkins FM. Patterns of food hypersensitivity during sixteen years of double-blind, placebo-controlled food challenges. J Pediatr. 1990 Oct;117(4):561-7.
http://www.ncbi.nlm.nih.gov/pubmed/2213379?tool=bestpractice.com
[10]Jansen JJ, Kardinaal AF, Huijbers G, et al. Prevalence of food allergy and intolerance in the adult Dutch population. J Allergy Clin Immunol. 1994 Feb;93(2):446-56.
http://www.ncbi.nlm.nih.gov/pubmed/8120272?tool=bestpractice.com
[11]Sicherer SH, Munoz-Furlong A, Sampson HA. Prevalence of peanut and tree nut allergy in the United States determined by means of a random digit dial telephone survey: a 5-year follow-up study. J Allergy Clin Immunol. 2003 Dec;112(6):1203-7.
http://www.ncbi.nlm.nih.gov/pubmed/14657884?tool=bestpractice.com
[12]Gupta RS, Warren CM, Smith BM, et al. The public health impact of parent-reported childhood food allergies in the United States. Pediatrics. 2018 Dec;142(6):e20181235.
https://pediatrics.aappublications.org/content/early/2018/11/15/peds.2018-1235.long
http://www.ncbi.nlm.nih.gov/pubmed/30455345?tool=bestpractice.com
It is seen more often in people with atopic dermatitis, certain pollen sensitivities, or latex sensitivity. The most common food allergens in young children in the US general population are cows' milk (2.5%), egg (1.3%), peanut (0.8%), wheat (approximately 0.4%), soy (approximately 0.4%), tree nuts (0.2%), fish (0.1%), and shellfish (0.1%).[1]Sicherer SH, Sampson HA. 9. Food allergy. J Allergy Clin Immunol. 2006 Feb;117(2 suppl Mini-Primer):S470-5.
https://www.jacionline.org/article/S0091-6749(05)01921-4/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/16455349?tool=bestpractice.com
Among US adults, the most commonly reported food allergens are shellfish (2.9%), milk (1.9%), peanut (1.8%), tree nut (1.2%), and fin fish (0.9%).[6]Gupta RS, Warren CM, Smith BM, et al. Prevalence and severity of food allergies among US adults. JAMA Netw Open. 2019 Jan 4;2(1):e185630.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324316
http://www.ncbi.nlm.nih.gov/pubmed/30646188?tool=bestpractice.com
Globally, prevalent allergens differ. For example, there is a higher incidence of sesame seed allergy in Israel, and of mustard allergy in France, and a lower incidence of peanut allergy in China.[2]Dalal I, Binson I, Levine A, et al. The pattern of sesame sensitivity among infants and children. Pediatr Allergy Immunol. 2003 Aug;14(4):312-6.
http://www.ncbi.nlm.nih.gov/pubmed/12911511?tool=bestpractice.com
[13]Rance F. Mustard allergy as a new food allergy. Allergy. 2003 Apr;58(4):287-8.
http://www.ncbi.nlm.nih.gov/pubmed/12708974?tool=bestpractice.com
[14]Beyer K, Morrow E, Li XM, et al. Effects of cooking methods on peanut allergenicity. J Allergy Clin Immunol. 2001 Jun;107(6):1077-81.
http://www.ncbi.nlm.nih.gov/pubmed/11398088?tool=bestpractice.com