Emerging treatments
Topiramate injection
Topiramate injection has received orphan-drug designation from the Food and Drug Administration (FDA) for the treatment of focal seizures or generalized tonic-clonic seizures in hospitalized epilepsy patients, or epilepsy patients being treated in an emergency care setting who are unable to take oral topiramate.[162]
Cannabidiol
Cannabidiol oral solution has been approved by the FDA and the European Medicines Agency for the treatment of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome. Multicenter, randomized, placebo-controlled trials are required to demonstrate efficacy in patients with generalized seizures.[163][164][165]
Seizure detection devices
Although still in developmental stages, there is evidence that implantable devices will be able to detect and prevent seizures before they occur. Use of such devices currently focuses on the recording of non-electroencephalography signals associated with tonic-clonic seizures in carefully selected patients.[166][167]
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